BIBX 1382 dihydrochloride | Tocris Bioscience 2416 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BIBX 1382 dihydrochloride

catalog :

2416

quantity :

1 mg (also 10 mg)

price :

117 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Xia M, Huang R, Sakamuru S, Alcorta D, Cho M, Lee D, et al. Identification of repurposed small molecule drugs for chordoma therapy. Cancer Biol Ther. 2013;14:638-47 pubmed publisher

product information

brand :

Tocris

master code :

2416

SKU :

2416/1

product name :

BIBX 1382 dihydrochloride

description :

Highly selective EGFR-kinase inhibitor

target :

EGF Receptor Inhibitors

category :

Small Molecules

unit size :

1 mg (also 10 mg)

purity :

97%

observed molecular weight :

460.77

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM). Displays 1000-fold lower potency against ErbB2 (IC50 = 3.4 u M) and a range of other related tyrosine kinases (IC50 10 u M). Oral administration inhibits growth of established human xenografts in athymic mice.

catalog number base :

2416

product keywords :

selective EGFR-kinases inhibitors inhibits Epidermal Growth Factors Receptors ErbB Her Receptor Tyrosine Kinases RTKs BIBX1382 dihydrochloride EGFR 2416,

extended description :

Highly selective EGFR-kinase inhibitor

chemical name text :

N8-(3-Chloro-4-fluorophenyl)-N2-(1-methyl-4-piperidinyl)-pyrimido[5,4-d]pyrimidine-2,8-diamine dihydrochloride

formula :

C 18 H 19 ClFN 7 .2HCl

formula text :

C18H19ClFN7.2HCl

cas num :

1216920-18-1

2020 USD :

113

2021 USD :

117 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage