HA 1100 hydrochloride | Tocris Bioscience 2415 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HA 1100 hydrochloride

catalog :

2415

quantity :

10 mg

price :

244 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Kirschstein T, Protzel C, Porath K, Sellmann T, Köhling R, Hakenberg O. Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro. Acta Pharmacol Sin. 2014;35:74-81 pubmed publisher
Pearn M, Hu Y, Niesman I, Patel H, Drummond J, Roth D, et al. Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation. Anesthesiology. 2012;116:352-61 pubmed publisher

product information

brand :

Tocris

master code :

2415

SKU :

2415/10

product name :

HA 1100 hydrochloride

description :

Cell-permeable, selective Rho-kinase inhibitor

target :

Rho-kinase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

99%

observed molecular weight :

343.83

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cell-permeable active metabolite of Fasudil (HA 1077; Cat. No. 0541). Produces ATP-competitive and reversible inhibition of Rho-kinase and is ~ 100-fold selective over a range of other protein kinases. Inhibits neutrophil migration and produces potent vasodilatory effects in vivo .

catalog number base :

2415

product keywords :

Cell-permeable selective Rho-kinase inhibitors inhibits Rho-Associated Coiled-Coil Kinases p160ROCK ROK Rho-Kinase HA1100 hydrochloride Hydroxyfasudil Rho-kinases 2415,

extended description :

Cell-permeable, selective Rho-kinase inhibitor

chemical name text :

1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride

formula :

C 14 H 17 N 3 O 3 S.HCl

formula text :

C14H17N3O3S.HCl

cas num :

155558-32-0

2020 USD :

244

2021 USD :

244 USD

alt names :

Hydroxyfasudil

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage