L-371,257 | Tocris Bioscience 2410 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-371,257

catalog :

2410

quantity :

10 mg

price :

269 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Lestanova Z, Puerta F, Alanazi M, Bacova Z, Kiss A, Castejon A, et al. Downregulation of Oxytocin Receptor Decreases the Length of Projections Stimulated by Retinoic Acid in the U-87MG Cells. Neurochem Res. 2017;42:1006-1014 pubmed publisher
Ataka K, Nagaishi K, Asakawa A, Inui A, Fujimiya M. Alteration of antral and proximal colonic motility induced by chronic psychological stress involves central urocortin 3 and vasopressin in rats. Am J Physiol Gastrointest Liver Physiol. 2012;303:G519-28 pubmed publisher

product information

brand :

Tocris

master code :

2410

SKU :

2410/10

product name :

L-371,257

description :

Potent and selective oxytocin receptor antagonist

target :

Oxytocin Receptor Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

99%

observed molecular weight :

507.59

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, high affinity human oxytocin (OT) receptor antagonist (Ki = 4.6 nM) that displays 800-fold selectivity over human arginine vasopressin receptors V1a and V2. Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Decreases length of U-87MG cell projections induced by retinoic acid (Cat.No.0695). Orally active.

catalog number base :

2410

product keywords :

Potent selective oxytocin receptors antagonists OT Receptors L371257 Oxytocin Receptors 2410,

extended description :

Potent and selective oxytocin receptor antagonist

chemical name text :

1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine

formula :

C 28 H 33 N 3 O 6

formula text :

C28H33N3O6

cas num :

162042-44-6

2020 USD :

258

2021 USD :

269 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage