FTI 277 | Tocris Bioscience 2407 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FTI 277

catalog :

2407

quantity :

1 mg

price :

148 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2407

SKU :

2407/1

product name :

FTI 277

description :

Prodrug form of FTI 276 (Cat. No. 2406)

target :

Other Transferase Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

95%

observed molecular weight :

561.64

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Prodrug form of FTI 276 (Cat. No. 2406) that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10 u M respectively) and disrupts constitutive H-Ras-specific activation of MAPK. Causes significant antiproliferative effects in human malignant glioma cells and many other tumor cell lines.

catalog number base :

2407

product keywords :

Prodrug FTI 276 2406 farnesyltransferase FTase H-Ras K-Ras MAPK anti-proliferative antiproliferative tumour tumor FTI277 Protein Prenyltransferases Post-translational Modifications 2407,

extended description :

Prodrug form of FTI 276 (Cat. No. 2406)

chemical name text :

N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt

formula :

C 22 H 29 N 3 O 3 S 2 .C 2 HF 3 O 2

formula text :

C22H29N3O3S2.C2HF3O2

cas num :

1217447-06-7

2020 USD :

145

2021 USD :

148 USD

storage :

Store at -80°C

more info or order :

Tocris Bioscience product webpage