FK 888 | Tocris Bioscience 2400/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FK 888

catalog :

2400/10

quantity :

10 mg

price :

377 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Mondal A, Aizawa S, Sakata I, Goswami C, Oda S, Sakai T. Mechanism of ghrelin-induced gastric contractions in Suncus murinus (house musk shrew): involvement of intrinsic primary afferent neurons. PLoS ONE. 2013;8:e60365 pubmed publisher

image

image 1 :

Cat.No. 2400 - FK 888 C36H36N4O4 CAS No. 138449-07-7

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2400

SKU :

2400/10

product name :

FK 888

Description :

High affinity NK1 antagonist

target :

NK1 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

588.69

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

FK 888 is a selective, high affinity tachykinin NK1 receptor antagonist (Ki = 0.69 nM) that displays 320-fold selectivity for human over rat NK1 receptors. Inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration.

extended description :

High affinity NK1 antagonist

chemical name text :

(4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide

formula :

C 36 H 36 N 4 O 4

formula text :

C36H36N4O4

cas num :

138449-07-7

USD :

377 USD

product details :

High affinity NK1 antagonist

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage