Eplerenone | Tocris Bioscience 2397 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Eplerenone

catalog :

2397

quantity :

10 mg (also 50 mg)

price :

163 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Ibrahim S, Xie W, Strong J, Tonello R, Berta T, Zhang J. Mineralocorticoid Antagonist Improves Glucocorticoid Receptor Signaling and Dexamethasone Analgesia in an Animal Model of Low Back Pain. Front Cell Neurosci. 2018;12:453 pubmed publisher
Urbanet R, Pilon C, Calcagno A, Peschechera A, Hubert E, Giacchetti G, et al. Analysis of insulin sensitivity in adipose tissue of patients with primary aldosteronism. J Clin Endocrinol Metab. 2010;95:4037-42 pubmed publisher

product information

brand :

Tocris

master code :

2397

SKU :

2397/10

product name :

Eplerenone

description :

Selective mineralocorticoid receptor antagonist

target :

Mineralocorticoid Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

414.5

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective mineralocorticoid (aldosterone) receptor antagonist (IC50 = 360 nM). Displays 27-fold selectivity over androgen, progesterone and estrogen receptors (IC50 10 u M). Orally active antihypertensive in vivo .

catalog number base :

2397

product keywords :

Selective mineralocorticoid receptor antagonists Aldosterone Receptors Inspra Epoxymexrenone Mineralocorticoid Receptor 2397,

extended description :

Selective mineralocorticoid receptor antagonist

chemical name text :

(7 ,11 ,17 )-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid -lactone methyl ester

formula :

C 24 H 30 O 6

formula text :

C24H30O6

cas num :

107724-20-9

2020 USD :

163

2021 USD :

163 USD

alt names :

Inspra, Epoxymexrenone

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage