EMD 386088 hydrochloride | Tocris Bioscience 2382/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

EMD 386088 hydrochloride

catalog :

2382/10

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Hirono M, Nagao S, Yanagawa Y, Konishi S. Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells. Neuropharmacology. 2017;118:79-89 pubmed publisher
Ly S, Pishdari B, Lok L, Hajos M, Kocsis B. Activation of 5-HT6 receptors modulates sleep-wake activity and hippocampal theta oscillation. ACS Chem Neurosci. 2013;4:191-9 pubmed publisher
Riccio O, Jacobshagen M, Golding B, Vutskits L, Jabaudon D, Hornung J, et al. Excess of serotonin affects neocortical pyramidal neuron migration. Transl Psychiatry. 2011;1:e47 pubmed publisher

image

image 1 :

Cat.No. 2382 - EMD 386088 hydrochloride C14H15N2Cl.HCl CAS No. 1171123-46-8

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2382

SKU :

2382/10

product name :

EMD 386088 hydrochloride

Description :

Potent 5-HT6 agonist

target :

5-HT6 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

283.2

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EMD 386088 hydrochloride is a potent 5-HT6 receptor agonist (EC50 = 1.0 nM) that displays selectivity over other 5-HT receptors (IC50 values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT6, 5-HT1D, 5-HT1B, 5-HT2A, 5-HT2C, 5-HT4, 5-HT1A and 5-HT7 receptors respectively). Shows moderate affinity at 5-HT3 receptors (IC50 = 34 nM).

extended description :

Potent 5-HT6 agonist

chemical name text :

5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole hydrochloride

formula :

C 14 H 15 N 2 Cl.HCl

formula text :

C14H15N2Cl.HCl

cas num :

1171123-46-8

USD :

208 USD

product details :

Potent 5-HT6 agonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage