ABT 702 hydrochloride | Tocris Bioscience 2372/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ABT 702 hydrochloride

catalog :

2372/10

quantity :

10 mg

price :

394 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Ahwazi D, Neopane K, Markby G, Kopietz F, Ovens A, Dall M, et al. Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965. Biochem J. 2021;478:2977-2997 pubmed publisher
Hobson B, Merritt K, Bachtell R. Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in rats. Neuropharmacology. 2012;63:1172-81 pubmed publisher
Fassett J, Hu X, Xu X, Lu Z, Zhang P, Chen Y, et al. Adenosine kinase regulation of cardiomyocyte hypertrophy. Am J Physiol Heart Circ Physiol. 2011;300:H1722-32 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2372

SKU :

2372/10

product name :

ABT 702 hydrochloride

description :

Adenosine kinase inhibitor; orally active

target :

Adenosine Kinase Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

499.79

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ABT 702 hydrochloride is a potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in animal models of pain and inflammation.

product keywords :

adenosines kinases inhibitors inhibits orally active ADK Receptors ABT702 hydrochloride Adenosine Kinase Other Adenosine 2372,

extended description :

Adenosine kinase inhibitor; orally active

chemical name text :

5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyrido[2,3-d]byrimidin-4-amine hydrochloride

formula :

C22H19N6OBr.HCl

formula text :

C22H19N6OBr.HCl

cas num :

2624336-92-9

USD :

382

USD 2025 :

394 USD

product details :

Adenosine kinase inhibitor; orally active

more info or order :

Tocris Bioscience product webpage