4-Methylhistamine dihydrochloride | Tocris Bioscience 2342/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4-Methylhistamine dihydrochloride

catalog :

2342/10

quantity :

10 mg (also 50 mg)

price :

271 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Glatzer F, Gschwandtner M, Ehling S, Rossbach K, Janik K, Klos A, et al. Histamine induces proliferation in keratinocytes from patients with atopic dermatitis through the histamine 4 receptor. J Allergy Clin Immunol. 2013;132:1358-67 pubmed publisher
Kim B, Kwon Y, Kim E, So I. Effects of histamine on cultured interstitial cells of cajal in murine small intestine. Korean J Physiol Pharmacol. 2013;17:149-56 pubmed publisher
Desmadryl G, Gaboyard Niay S, Brugeaud A, Travo C, Broussy A, Saleur A, et al. Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability. Br J Pharmacol. 2012;167:905-16 pubmed publisher
Connelly W, Shenton F, Lethbridge N, Leurs R, Waldvogel H, Faull R, et al. The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS. Br J Pharmacol. 2009;157:55-63 pubmed publisher
Holden N, Gong W, King E, Kaur M, Giembycz M, Newton R. Potentiation of NF-kappaB-dependent transcription and inflammatory mediator release by histamine in human airway epithelial cells. Br J Pharmacol. 2007;152:891-902 pubmed

image

image 1 :

Cat.No. 2342 - 4-Methylhistamine dihydrochloride C6H11N3.2HCl CAS No. 36376-47-3

product information

brand :

Tocris

catalog number base :

2342

SKU :

2342/10

product name :

4-Methylhistamine dihydrochloride

units size :

10 mg (also 50 mg)

description :

Selective, high affinity H4 agonist

target :

Histamine H4 Receptor Agonists

category :

Small Molecules

observed molecular weight :

198.09

url print :

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details of functionality :

4-Methylhistamine dihydrochloride is a potent, high affinity H4 receptor agonist (Ki = 7 nM) that displays 100-fold selectivity over other human histamine receptor subtypes.

top caption :

Selective, high affinity H4 agonist

extended description :

Selective, high affinity H4 agonist

chemical name text :

5-(2-Aminoethyl)-4-methylimidazole dihydrochloride

formula :

C6H11N3.2HCl

formula text :

C6H11N3.2HCl

cas num :

36376-47-3

USD :

271 USD

product details :

Selective, high affinity H4 agonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage