DMP 543 | Tocris Bioscience 2330 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DMP 543

catalog :

2330

quantity :

10 mg (also 50 mg)

price :

136 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ipavec V, Martire M, Barrese V, Taglialatela M, Curro D. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus. Pharmacol Res. 2011;64:397-409 pubmed publisher

product information

brand :

Tocris

master code :

2330

SKU :

2330/10

product name :

DMP 543

description :

Potent, orally active ACh release enhancer

target :

Two-P Potassium Channels Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

412.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Acetylcholine release stimulator. Potently enhances K+-stimulated [3H]-ACh release from rat hippocampal slices (EC50 = 700 nM), and increases release of dopamine and glutamate (EC50 values are 0.25 and 0.22 u M, respectively). Orally active in vivo ; increases ACh levels in rats (with a minimum effective dose of 1 mg/kg) and exerts a long duration of action. More potent than linopirdine (Cat. No. 1999) both in vitro and in vivo . Also K+ channel blocker.

catalog number base :

2330

product keywords :

K+ channels blockers potent ACh release enhancer Potent orally active Potassium Channels Non-Selective Acetylcholine Nicotinic Receptors nAChR Muscarinic DMP543 Other Acetylcholine Non-selective Muscarinics Voltage-Gated Potassium Channels 2330,

extended description :

Potent, orally active ACh release enhancer

chemical name text :

10,10-bis[(2-Fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone

formula :

C 26 H 18 F 2 N 2 O

formula text :

C26H18F2N2O

cas num :

160588-45-4

2020 USD :

136

2021 USD :

136 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage