product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Pravastatin sodium salt
catalog :
2318
quantity :
50 mg
price :
128 USD
more info or order :
citations: 3
Reference
Ding Y, Zhang M, Zhang W, Lu Q, Cai Z, Song P, et al. AMP-Activated Protein Kinase Alpha 2 Deletion Induces VSMC Phenotypic Switching and Reduces Features of Atherosclerotic Plaque Stability. Circ Res. 2016;119:718-30 pubmed publisher
Rojo Arreola L, Long T, Asarnow D, Suzuki B, Singh R, Caffrey C. Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis. PLoS ONE. 2014;9:e87594 pubmed publisher
Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppanen Laakso T, Virtanen J, et al. Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins. Oncotarget. 2011;2:1176-90 pubmed
product information
brand :
Tocris
master code :
2318
SKU :
2318/50
product name :
Pravastatin sodium salt
description :
HMG-CoA reductase inhibitor
target :
HMG-CoA Reductase Inhibitors
category :
Small Molecules
unit size :
50 mg
purity :
98%
observed molecular weight :
446.51
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties.
catalog number base :
2318
product keywords :
HMG-CoA reductases inhibitors inhibits statins Eptastatin sodium HMG-CoA Reductase 2318,
extended description :
HMG-CoA reductase inhibitor
chemical name text :
( R, R,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro- , ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt
formula :
C 23 H 35 NaO 7
formula text :
C23H35NaO7
cas num :
81131-70-6
2020 USD :
124
2021 USD :
128 USD
alt names :
Eptastatin sodium
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK