DNQX disodium salt | Tocris Bioscience 2312/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DNQX disodium salt

catalog :

2312/10

quantity :

10 mg (also 50 mg)

price :

98 USD

more info or order :

Tocris Bioscience product webpage

citations: 8

Reference
Li K, He M, Ye W, Simms J, Gill M, Xiang X, et al. TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala. elife. 2019;8: pubmed publisher
Loo L, Simon J, Xing L, McCoy E, Niehaus J, Guo J, et al. Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019;10:134 pubmed publisher
Abrahao K, Chancey J, Chan C, Lovinger D. Ethanol-Sensitive Pacemaker Neurons in the Mouse External Globus Pallidus. Neuropsychopharmacology. 2017;42:1070-1081 pubmed publisher
Pan G, Yang J, Hu X, Li X. Postnatal development of the electrophysiological properties of somatostatin interneurons in the anterior cingulate cortex of mice. Sci Rep. 2016;6:28137 pubmed publisher
Dilger E, Krahe T, Morhardt D, Seabrook T, Shin H, Guido W. Absence of plateau potentials in dLGN cells leads to a breakdown in retinogeniculate refinement. J Neurosci. 2015;35:3652-62 pubmed publisher
Tseng W, Jenkins P, Tanaka M, Mooney R, Bennett V. Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABAA receptors. Proc Natl Acad Sci U S A. 2015;112:1214-9 pubmed publisher
Lindstrom S, Azizi N, Weller C, Wilson M. Retinal input to efferent target amacrine cells in the avian retina. Vis Neurosci. 2010;27:103-18 pubmed publisher
Linnemann C, Schmeh I, Thier P, Schwarz C. Transient change in GABA(A) receptor subunit mRNA expression in Lurcher cerebellar nuclei during Purkinje cell degeneration. BMC Neurosci. 2006;7:59 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2312

SKU :

2312/10

product name :

DNQX disodium salt

description :

Selective non-NMDA iGluR antagonist; water-soluble salt of DNQX (Cat. No. 0189)

target :

AMPA Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Desiccate at RT

observed molecular weight :

296.1

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DNQX disodium salt is a more water-soluble form of DNQX (Cat. No. 0189). DNQX is a selective non-NMDA glutamate receptor antagonist. (IC50 = 0.1 M and 0.5 M for kainate and AMPA receptors, respectively). DNQX is a neuroleptic agent that shows pro-oxidative properties. DNQX selectively depolarizes rat thalamic reticular nucleus neurons.

product keywords :

Water-soluble salt Glutamate Kainate Receptors iGluR Ionotropic AMPA non-NMDA neuroleptic antagonists AMPA Receptors Kainate Receptors 2312,

extended description :

Selective non-NMDA iGluR antagonist; water-soluble salt of DNQX (Cat. No. 0189)

chemical name text :

6,7-Dinitroquinoxaline-2,3-dione disodium salt

formula :

C8H2N4O6Na2

formula text :

C8H2N4O6Na2

cas num :

1312992-24-7

USD :

USD 2025 :

98 USD

product details :

Selective non-NMDA iGluR antagonist; water-soluble salt of DNQX (Cat. No. 0189)

more info or order :

Tocris Bioscience product webpage