product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
T 0070907
catalog :
2301/5
quantity :
5 mg (also 25 mg)
price :
118 USD
more info or order :
citations: 7
Reference
Fellous T, De Maio F, Kalkan H, Carannante B, Boccella S, Petrosino S, et al. Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets. Biochem Pharmacol. 2020;175:113859 pubmed publisher
Saito Y, Nakamura K, Miura D, Yunoki K, Miyoshi T, Yoshida M, et al. Suppression of Wnt Signaling and Osteogenic Changes in Vascular Smooth Muscle Cells by Eicosapentaenoic Acid. Nutrients. 2017;9: pubmed publisher
Kassotis C, Masse L, Kim S, Schlezinger J, Webster T, Stapleton H. Characterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling. Sci Rep. 2017;7:42104 pubmed publisher
Chung J, Park J, Yun J, Kang Y, Park B, Hwang S, et al. Cultured Human Periosteum-Derived Cells Can Differentiate into Osteoblasts in a Perioxisome Proliferator-Activated Receptor Gamma-Mediated Fashion via Bone Morphogenetic Protein signaling. Int J Med Sci. 2016;13:806-818 pubmed
Bullers S, Baker S, Ingham E, Southgate J. The human tissue-biomaterial interface: a role for PPAR?-dependent glucocorticoid receptor activation in regulating the CD163+ M2 macrophage phenotype. Tissue Eng Part A. 2014;20:2390-401 pubmed publisher
Hamtiaux L, Masquelier J, Muccioli G, Bouzin C, Feron O, Gallez B, et al. The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action. BMC Cancer. 2012;12:92 pubmed publisher
Hamtiaux L, Hansoulle L, Dauguet N, Muccioli G, Gallez B, Lambert D. Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. PLoS ONE. 2011;6:e26823 pubmed publisher
image
image 1 :
Tocris Bioscience 2301/5 image 1
Cat.No. 2301 - T 0070907 C12H8N3O3Cl CAS No. 313516-66-4
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2301
SKU :
2301/5
product name :
T 0070907
description :
Highly potent and selective covalent PPAR antagonist
target :
PPAR gamma Receptor Antagonists
unit size :
5 mg (also 25 mg)
category :
Small Molecules
purity :
99%
storage :
Store at RT
observed molecular weight :
277.67
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
T 0070907 is a potent and selective irreversible PPAR antagonist (IC50 = 1 nM). Displays 800-fold selectivity for PPAR over PPAR and PPAR . Blocks transcriptional activity of PPAR in vitro and inhibits Rosiglitazone -induced adipogenesis.
product keywords :
potent selective PPAR PPARgamma antagonists Peroxisome Proliferator-activating Receptors T0070907 PPARgamma Receptors 2301,
extended description :
Highly potent and selective covalent PPAR antagonist
chemical name text :
2-Chloro-5-nitro-N-4-pyridinylbenzamide
formula :
C12H8N3O3Cl
formula text :
C12H8N3O3Cl
cas num :
313516-66-4
USD :
116
USD 2025 :
118 USD
product details :
Highly potent and selective covalent PPAR antagonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK