product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SCH 39166 hydrobromide
catalog :
2299/10
quantity :
10 mg (also 50 mg)
price :
287 USD
more info or order :
citations: 6
Reference
Lim G, Kim H, McCabe M, Chou C, Wang S, Chen L, et al. A leptin-mediated central mechanism in analgesia-enhanced opioid reward in rats. J Neurosci. 2014;34:9779-88 pubmed publisher
Fleischmann K, Pagel P, Schmid I, Roscher A. RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes. Mol Cancer. 2014;13:27 pubmed publisher
Zheng H, Liu X, Li Y, Mishra P, Patel K. Attenuated dopaminergic tone in the paraventricular nucleus contributing to sympathoexcitation in rats with Type 2 diabetes. Am J Physiol Regul Integr Comp Physiol. 2014;306:R138-48 pubmed publisher
Mizuta K, Zhang Y, Xu D, Mizuta F, D Ovidio F, Masaki E, et al. The dopamine D1 receptor is expressed and facilitates relaxation in airway smooth muscle. Respir Res. 2013;14:89 pubmed publisher
Nunes E, Randall P, Santerre J, Given A, Sager T, Correa M, et al. Differential effects of selective adenosine antagonists on the effort-related impairments induced by dopamine D1 and D2 antagonism. Neuroscience. 2010;170:268-80 pubmed publisher
Sink K, Vemuri V, Olszewska T, Makriyannis A, Salamone J. Cannabinoid CB1 antagonists and dopamine antagonists produce different effects on a task involving response allocation and effort-related choice in food-seeking behavior. Psychopharmacology (Berl). 2008;196:565-74 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2299
SKU :
2299/10
product name :
SCH 39166 hydrobromide
description :
High affinity D1-like antagonist
target :
Dopamine D1 and D5 Receptor Antagonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Desiccate at RT
observed molecular weight :
394.73
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SCH 39166 hydrobromide is a high affinity dopamine D1/D5 receptor antagonist; displays Ki values of 1.2, 2, 980, 5520, 80 and 731 nM for binding to D1, D5, D2, D4, 5-HT and 2a receptors, respectively.
product keywords :
High affinity D1/D5 receptor antagonists Dopamine Receptors dopaminergic SCH39166 hydrobromide Ecopipam hydrobromide D1 and D5 Receptors 2299,
extended description :
High affinity D1-like antagonist
chemical name text :
(6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide
formula :
C19H20ClNO.HBr
formula text :
C19H20ClNO.HBr
cas num :
1227675-51-5
USD :
278
USD 2025 :
287 USD
product details :
High affinity D1-like antagonist
alt names :
Ecopipam hydrobromide
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK