Prostaglandin E2 | Tocris Bioscience 2296 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Prostaglandin E2

catalog :

2296

quantity :

10 mg

price :

165 USD

more info or order :

Tocris Bioscience product webpage

citations: 19

Reference
Post Y, Puschhof J, Beumer J, Kerkkamp H, de Bakker M, Slagboom J, et al. Snake Venom Gland Organoids. Cell. 2020;180:233-247.e21 pubmed publisher
Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Sole L, et al. IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer. Mol Cell. 2019;75:669-682.e5 pubmed publisher
Somerville T, Xu Y, Miyabayashi K, Tiriac H, Cleary C, Maia Silva D, et al. TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Cell Rep. 2018;25:1741-1755.e7 pubmed publisher
Senger S, Ingano L, Freire R, Anselmo A, Zhu W, Sadreyev R, et al. Human Fetal-Derived Enterospheres Provide Insights on Intestinal Development and a Novel Model to Study Necrotizing Enterocolitis (NEC). Cell Mol Gastroenterol Hepatol. 2018;5:549-568 pubmed publisher
Sherman H, Gitschier H, Rossi A. A Novel Three-Dimensional Immune Oncology Model for High-Throughput Testing of Tumoricidal Activity. Front Immunol. 2018;9:857 pubmed publisher
Ye Y, Vattai A, Ditsch N, Kuhn C, Rahmeh M, Mahner S, et al. Prostaglandin E2 receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses. Endocr Connect. 2018;7:749-761 pubmed publisher
Zhu J, Trillsch F, Mayr D, Kuhn C, Rahmeh M, Hofmann S, et al. Prostaglandin receptor EP3 regulates cell proliferation and migration with impact on survival of endometrial cancer patients. Oncotarget. 2018;9:982-994 pubmed publisher
Sachamitr P, Leishman A, Davies T, Fairchild P. Directed Differentiation of Human Induced Pluripotent Stem Cells into Dendritic Cells Displaying Tolerogenic Properties and Resembling the CD141+ Subset. Front Immunol. 2017;8:1935 pubmed publisher
Ma L, Li J, Nie Q, Zhang Q, Liu S, Ge D, et al. Organoid culture of human prostate cancer cell lines LNCaP and C4-2B. Am J Clin Exp Urol. 2017;5:25-33 pubmed
Roe J, Hwang C, Somerville T, Milazzo J, Lee E, Da Silva B, et al. Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis. Cell. 2017;170:875-888.e20 pubmed publisher
Langdale C, Hokanson J, Sridhar A, Grill W. Stimulation of the pelvic nerve increases bladder capacity in the prostaglandin E2 rat model of overactive bladder. Am J Physiol Renal Physiol. 2017;313:F657-F665 pubmed publisher
Al Taei S, Salimu J, Spary L, Clayton A, Lester J, Tabi Z. Prostaglandin E2-mediated adenosinergic effects on CD14+ cells: Self-amplifying immunosuppression in cancer. Oncoimmunology. 2017;6:e1268308 pubmed publisher
Drost J, Karthaus W, Gao D, Driehuis E, Sawyers C, Chen Y, et al. Organoid culture systems for prostate epithelial and cancer tissue. Nat Protoc. 2016;11:347-58 pubmed publisher
Weeber F, van de Wetering M, Hoogstraat M, Dijkstra K, Krijgsman O, Kuilman T, et al. Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases. Proc Natl Acad Sci U S A. 2015;112:13308-11 pubmed publisher
Gonnermann D, Oberg H, Kellner C, Peipp M, Sebens S, Kabelitz D, et al. Resistance of cyclooxygenase-2 expressing pancreatic ductal adenocarcinoma cells against Î³Î´ T cell cytotoxicity. Oncoimmunology. 2015;4:e988460 pubmed
Boj S, Hwang C, Baker L, Chio I, Engle D, Corbo V, et al. Organoid models of human and mouse ductal pancreatic cancer. Cell. 2015;160:324-38 pubmed publisher
Bartfeld S, Bayram T, van de Wetering M, Huch M, Begthel H, Kujala P, et al. In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. Gastroenterology. 2015;148:126-136.e6 pubmed publisher
Anneken J, Cunningham J, Collins S, Yamamoto B, Gudelsky G. MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. J Neuroimmune Pharmacol. 2013;8:58-65 pubmed publisher
Wang F, Smith N, Xu Q, Fujita T, Baba A, Matsuda T, et al. Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+. Sci Signal. 2012;5:ra26 pubmed publisher

product information

brand :

Tocris

master code :

2296

SKU :

2296/10

product name :

Prostaglandin E2

description :

Major endogenous prostanoid

target :

Prostanoid Receptor Agonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

352.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Binds with high affinity to EP1, EP2, EP3 and EP4 receptors (Kd values range between ~ 1 - 10 nM). Influences a wide range of processes including inflammation, smooth muscle relaxation, fertility and gastric mucosal integrity. Regulates vertebrate hematopoietic stem cell (HSC) homeostasis. Acts as viral transduction enhancer.

catalog number base :

2296

product keywords :

endogenous prostanoid EP1 EP2 EP3 EP4 Receptors prostaglandins prostacyclins eicosanoids ProstaglandinE2 stem cells e2 PGE2 PGE2 Prostanoid Receptors Stem Cell Signaling Stem Cell Proliferation Organoids Viral Transduction Enhancers 2296,

extended description :

Major endogenous prostanoid

chemical name text :

(5Z,11 ,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1oic acid

formula :

C 20 H 32 O 5

formula text :

C20H32O5

cas num :

363-24-6

2020 USD :

157

2021 USD :

165 USD

alt names :

PGE2

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage