K-252c | Tocris Bioscience 2287 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

K-252c

catalog :

2287

quantity :

1 mg

price :

177 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Goldman P, Ryan K, Hamill M, Howard Jones A, Walsh C, Elliott S, et al. An unusual role for a mobile flavin in StaC-like indolocarbazole biosynthetic enzymes. Chem Biol. 2012;19:855-65 pubmed publisher

product information

brand :

Tocris

master code :

2287

SKU :

2287/1

product name :

K-252c

description :

Protein kinase C inhibitor

target :

Protein Kinase C Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

99%

observed molecular weight :

311.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of protein kinase C (IC50 = 2.45 u M) that displays ~ 10-fold selectivity over protein kinase A (IC50 = 25.7 u M). Also inhibits -lactamase, malate dehydrogenase and chymotrypsin (IC50 values are 8, 8 and 10 u M respectively). Exhibits antiviral activity against GCV-sensitive and -resistant strains of human cytomegalovirus (HCMV) (IC50 values range from 0.13 - 0.32 u M). Shows no activity against herpes simplex virus (HSV).

catalog number base :

2287

product keywords :

Protein kinases C inhibitors inhibits PKC Staurosporinone Protein Kinase C Cytomegalovirus 2287,

extended description :

Protein kinase C inhibitor

chemical name text :

6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

formula :

C 20 H 13 N 3 O

formula text :

C20H13N3O

cas num :

85753-43-1

2020 USD :

173

2021 USD :

177 USD

alt names :

Staurosporinone

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage