2'-MeCCPA | Tocris Bioscience 2281 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

2'-MeCCPA

catalog :

2281

quantity :

10 mg

price :

287 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Liu G, Zhang W, Guo J, Kong F, Zhou S, Chen S, et al. Adenosine binds predominantly to adenosine receptor A1 subtype in astrocytes and mediates an immunosuppressive effect. Brain Res. 2018;1700:47-55 pubmed publisher
Yang A, Mucsi A, Desrosiers M, Chen J, Schnermann J, Blackburn M, et al. Adenosine mediated desensitization of cAMP signaling enhances T-cell responses. Eur J Immunol. 2010;40:449-59 pubmed publisher

product information

brand :

Tocris

master code :

2281

SKU :

2281/10

product name :

2'-MeCCPA

description :

Very selective and potent A1 receptor agonist

target :

Adenosine A1 Receptor Agonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

383.83

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and highly selective agonist at A1 adenosine receptors (Ki values are 3.3, 9580, 37600 and 1150 nM for human recombinant A1, A2A, A2B and A3 receptors respectively). Acts as a full agonist; inhibits forskolin-stimulated adenylyl cyclase activity in rat cortical membranes with an IC50 value of 13.1 nM.

catalog number base :

2281

product keywords :

selective potent A1 receptor agonists Receptors adenosines 2-MeCCPA Adenosine A1 Receptors 2281,

extended description :

Very selective and potent A1 receptor agonist

chemical name text :

2-Chloro-N-cyclopentyl-2 -methyladenosine

formula :

C 16 H 22 ClN 5 O 4

formula text :

C16H22ClN5O4

cas num :

205171-12-6

2020 USD :

278

2021 USD :

287 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage