2'-MeCCPA | Tocris Bioscience 2281/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

2'-MeCCPA

catalog :

2281/10

quantity :

10 mg

price :

360 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Liu G, Zhang W, Guo J, Kong F, Zhou S, Chen S, et al. Adenosine binds predominantly to adenosine receptor A1 subtype in astrocytes and mediates an immunosuppressive effect. Brain Res. 2018;1700:47-55 pubmed publisher
Yang A, Mucsi A, Desrosiers M, Chen J, Schnermann J, Blackburn M, et al. Adenosine mediated desensitization of cAMP signaling enhances T-cell responses. Eur J Immunol. 2010;40:449-59 pubmed publisher

image

image 1 :

Cat.No. 2281 - 2 -MeCCPA C16H22ClN5O4 CAS No. 205171-12-6

product information

brand :

Tocris

catalog number base :

2281

SKU :

2281/10

product name :

2'-MeCCPA

units size :

10 mg

description :

Highly selective and potent A1 receptor agonist

target :

Adenosine A1 Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

383.83

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

2 -MeCCPA is a potent and highly selective agonist at A1 adenosine receptors (Ki values are 3.3, 9580, 37600 and 1150 nM for human recombinant A1, A2A, A2B and A3 receptors respectively). Acts as a full agonist; inhibits forskolin-stimulated adenylyl cyclase activity in rat cortical membranes with an IC50 value of 13.1 nM.

top caption :

Highly selective and potent A1 receptor agonist

extended description :

Highly selective and potent A1 receptor agonist

chemical name text :

2-Chloro-N-cyclopentyl-2 -methyladenosine

formula :

C16H22ClN5O4

formula text :

C16H22ClN5O4

cas num :

205171-12-6

USD :

360 USD

product details :

Highly selective and potent A1 receptor agonist

storage :

Store at +4Â°C

more info or order :

Tocris Bioscience product webpage