Raloxifene hydrochloride | Tocris Bioscience 2280/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Raloxifene hydrochloride

catalog :

2280/50

quantity :

50 mg

price :

124 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Morikawa N, Kato Y, Takeshita N, Shimizu Y. Pharmacological characterization of AS2690168, a novel small molecule RANKL signal transduction inhibitor. Eur J Pharmacol. 2022;924:174941 pubmed publisher
Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, et al. Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. Proc Natl Acad Sci U S A. 2018;115:E7795-E7804 pubmed publisher
Nicholson T, Moses M, Uchtmann K, Keil K, Bjorling D, Vezina C, et al. Estrogen receptor-Î± is a key mediator and therapeutic target for bladder complications of benign prostatic hyperplasia. J Urol. 2015;193:722-9 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2280

SKU :

2280/50

product name :

Raloxifene hydrochloride

description :

Selective estrogen receptor modulator (SERM)

target :

Estrogen and Related Receptor Modulators

unit size :

50 mg

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

510.04

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM) that binds to ER and ER , and tissue-dependently activates or blocks estrogen-induced transcription. Acts as an antiestrogen in breast and uterine tissue, but displays estrogen agonist activity in bone. In D12 rat hypothalamic cells, inhibits progesterone receptor induction by estrogen with an IC50 of 1 nM.

product keywords :

Selective estrogen receptor modulators SERM ER Estrogen Receptors LY139481 amino acid transporter 2 ASCT2 LY 139481 Keoxifene Estrogen and Related Receptors 2280,

extended description :

Selective estrogen receptor modulator (SERM)

chemical name text :

[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone hydrochloride

formula :

C28H27NO4S.HCl

formula text :

C28H27NO4S.HCl

cas num :

82640-04-8

USD :

119

USD 2025 :

124 USD

product details :

Selective estrogen receptor modulator (SERM)

alt names :

LY 139481,Keoxifene

more info or order :

Tocris Bioscience product webpage