CGS 9343B | Tocris Bioscience 2255 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CGS 9343B

catalog :

2255

quantity :

10 mg

price :

229 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Haag N, Schüler S, Nietzsche S, Hübner C, Strenzke N, Qualmann B, et al. The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea. Cell Rep. 2018;24:2418-2431.e6 pubmed publisher
Hou W, Izadi M, Nemitz S, Haag N, Kessels M, Qualmann B. The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin. PLoS Biol. 2015;13:e1002233 pubmed publisher

product information

brand :

Tocris

master code :

2255

SKU :

2255/10

product name :

CGS 9343B

description :

Calmodulin antagonist

target :

Calcium Binding Protein Modulator Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

544.61

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Calmodulin antagonist; inhibits calmodulin-stimulated cAMP phosphodiesterase activity with an IC50 of 3.3 nM. Also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR.

catalog number base :

2255

product keywords :

Calmodulin antagonists Ca2+ Binding Protein modulators Calcium Signaling Signalling CGS9343B Zaldaride maleate Calcium Binding Protein 2255,

extended description :

Calmodulin antagonist

chemical name text :

1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate

formula :

C 26 H 28 N 4 O 2 .C 4 H 4 O 4

formula text :

C26H28N4O2.C4H4O4

cas num :

109826-27-9

2020 USD :

222

2021 USD :

229 USD

alt names :

Zaldaride maleate

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage