CGS 9343B | Tocris Bioscience 2255/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CGS 9343B

catalog :

2255/10

quantity :

10 mg

price :

287 USD

citations: 2

Reference
Haag N, Schüler S, Nietzsche S, Hübner C, Strenzke N, Qualmann B, et al. The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea. Cell Rep. 2018;24:2418-2431.e6 pubmed publisher
Hou W, Izadi M, Nemitz S, Haag N, Kessels M, Qualmann B. The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin. PLoS Biol. 2015;13:e1002233 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2255

SKU :

2255/10

product name :

CGS 9343B

description :

Calmodulin antagonist

target :

Calcium Binding Protein Modulator Antagonists

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Desiccate at RT

observed molecular weight :

544.61

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CGS 9343B is a calmodulin antagonist; inhibits calmodulin-stimulated cAMP phosphodiesterase activity with an IC50 of 3.3 nM. Also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR.

product keywords :

Calmodulin antagonists Ca2+ Binding Protein modulators Calcium Signaling Signalling CGS9343B Zaldaride maleate Calcium Binding Protein 2255,

extended description :

Calmodulin antagonist

chemical name text :

1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate

formula :

C26H28N4O2.C4H4O4

formula text :

C26H28N4O2.C4H4O4

cas num :

109826-27-9

USD :

284

USD 2025 :

287 USD

product details :

Calmodulin antagonist

alt names :

Zaldaride maleate