BRL 50481 | Tocris Bioscience 2237/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BRL 50481

catalog :

2237/10

quantity :

10 mg (also 50 mg)

price :

146 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Zhai K, Hubert F, Nicolas V, Ji G, Fischmeister R, Leblais V. ?-Adrenergic cAMP signals are predominantly regulated by phosphodiesterase type 4 in cultured adult rat aortic smooth muscle cells. PLoS ONE. 2012;7:e47826 pubmed publisher
Morales Garcia J, Redondo M, Alonso Gil S, Gil C, Perez C, Martinez A, et al. Phosphodiesterase 7 inhibition preserves dopaminergic neurons in cellular and rodent models of Parkinson disease. PLoS ONE. 2011;6:e17240 pubmed publisher
Meyers J, Su D, Lerner A. Chronic lymphocytic leukemia and B and T cells differ in their response to cyclic nucleotide phosphodiesterase inhibitors. J Immunol. 2009;182:5400-11 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2237

SKU :

2237/10

product name :

BRL 50481

description :

Selective PDE7 inhibitor

target :

Phosphodiesterase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

244.26

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BRL 50481 is a selective, substrate-competitive inhibitor of phosphodiesterase (PDE) 7 (Ki = 180 nM). Displays 200-fold selectivity over PDE1B, PDE1C, PDE2, PDE3, PDE4A4 and PDE5.

product keywords :

Selective PDE7 inhibitors inhibits Phosphodiesterases BRL50481 GlaxoSmithKline GSK Phosphodiesterases 2237,

extended description :

Selective PDE7 inhibitor

chemical name text :

N,N,2-Trimethyl-5-nitro-benzenesulfonamide

formula :

C9H12N2O4S

formula text :

C9H12N2O4S

cas num :

433695-36-4

USD :

144

USD 2025 :

146 USD

product details :

Selective PDE7 inhibitor

more info or order :

Tocris Bioscience product webpage