CI 976 | Tocris Bioscience 2227/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CI 976

catalog :

2227/10

quantity :

10 mg (also 50 mg)

price :

232 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Pagliuso A, Valente C, Giordano L, Filograna A, Li G, Circolo D, et al. Golgi membrane fission requires the CtBP1-S/BARS-induced activation of lysophosphatidic acid acyltransferase ?. Nat Commun. 2016;7:12148 pubmed publisher
Schmidt J, Brown W. Lysophosphatidic acid acyltransferase 3 regulates Golgi complex structure and function. J Cell Biol. 2009;186:211-8 pubmed publisher

product information

brand :

Tocris

catalog number base :

2227

SKU :

2227/10

product name :

CI 976

units size :

10 mg (also 50 mg)

description :

Selective ACAT inhibitor

target :

Acyl-CoA:Cholesterol Acyltransferase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

393.57

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CI 976 is a selective acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor (IC50 = 0.073 u M). Lowers non-high density lipoprotein (HDL)-cholesterol and increases HDL-cholesterol concentrations in rats with pre-established dyslipidemia. Orally active. Also inhibits Golgi-associated LPL acyltransferase (LPAT) activity (IC50 = 15 M).

top caption :

Selective ACAT inhibitor

extended description :

Selective ACAT inhibitor

chemical name text :

2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide

formula :

C23H39NO4

formula text :

C23H39NO4

cas num :

114289-47-3

USD :

232 USD

product details :

Selective ACAT inhibitor

storage :

Store at +4Â°C

more info or order :

Tocris Bioscience product webpage