Rac1 Inhibitor W56 | Tocris Bioscience 2221 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Rac1 Inhibitor W56

catalog :

2221

quantity :

1 mg

price :

235 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
De Bessa T, Pagano A, Moretti A, Oliveira P, Mendonça S, Kovacic H, et al. Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas. Cell Death Dis. 2019;10:143 pubmed publisher
Ikram M, Lim Y, Baek S, Jin S, Jeong Y, Kwak J, et al. Co-targeting of Tiam1/Rac1 and Notch ameliorates chemoresistance against doxorubicin in a biomimetic 3D lymphoma model. Oncotarget. 2018;9:2058-2075 pubmed publisher
Kruppa A, Kishi Itakura C, Masters T, Rorbach J, Grice G, Kendrick Jones J, et al. Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell. 2018;44:484-499.e6 pubmed publisher
Zeineddine R, Pundavela J, Corcoran L, Stewart E, Do Ha D, Bax M, et al. SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation. Mol Neurodegener. 2015;10:57 pubmed publisher

product information

brand :

Tocris

master code :

2221

SKU :

2221/1

product name :

Rac1 Inhibitor W56

description :

Selective inhibitor of Rac1-GEF interaction

target :

Rho GTPase Inhibitors

category :

Peptides

unit size :

1 mg

observed molecular weight :

1671.93

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. . Control Peptide also available.

catalog number base :

2221

product keywords :

Selective inhibitors inhibits Rac1-GEF interaction GTPases G Proteins Small Rho 2221,

extended description :

Selective inhibitor of Rac1-GEF interaction

formula :

C 74 H 117 N 19 O 23 S

formula text :

C74H117N19O23S

cas num :

1095179-01-3

2020 USD :

228

2021 USD :

235 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage