Zatebradine hydrochloride | Tocris Bioscience 2202/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Zatebradine hydrochloride

catalog :

2202/10

quantity :

10 mg (also 50 mg)

price :

236 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Bender R, Kirschstein T, Kretz O, Brewster A, Richichi C, Rüschenschmidt C, et al. Localization of HCN1 channels to presynaptic compartments: novel plasticity that may contribute to hippocampal maturation. J Neurosci. 2007;27:4697-706 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2202

SKU :

2202/10

product name :

Zatebradine hydrochloride

description :

Blocks hyperpolarization-activated current (If)

target :

Ion Channel Modulators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Desiccate at +4°C

observed molecular weight :

493.04

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Zatebradine hydrochloride is a bradycardic agent that produces use-dependent inhibition of hyperpolarization-activated current If (HCN channel) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres. Displays negative chronotropic activity in isolated guinea pig atria (EC50 of 13.4 u M).

product keywords :

Bradycardic agent blocks If pacemaker current Channel modulators VDAC ULFS49 HCN blockers UL-FS 49 HCN Channels 2202,

extended description :

Blocks hyperpolarization-activated current (If)

chemical name text :

3-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride

formula :

C26H36N2O5.HCl

formula text :

C26H36N2O5.HCl

cas num :

91940-87-3

USD :

229

USD 2025 :

236 USD

product details :

Blocks hyperpolarization-activated current (If)

alt names :

UL-FS 49

more info or order :

Tocris Bioscience product webpage