R 59-022 | Tocris Bioscience 2194 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

R 59-022

catalog :

2194

quantity :

10 mg (also 50 mg)

price :

162 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Conley J, Meyer J, Nuss A, Doyle T, Savinov S, Hill C, et al. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. J Pharmacol Exp Ther. 2015;352:53-60 pubmed publisher

product information

brand :

Tocris

master code :

2194

SKU :

2194/10

product name :

R 59-022

description :

Diacylglycerol kinase inhibitor; increases PKC activity

target :

Lipid Metabolism Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

459.58

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 u M); increases protein kinase C activity. Potentiates thrombin-induced platelet aggregation and induces neutrophil chemotaxis. Inhibits U46619-induced contractions in mouse aorta and porcine coronary artery.

catalog number base :

2194

product keywords :

Diacylglycerol kinase inhibitors inhibits increases PKC activity DGK DAG Kinase Kinases Lipid Metabolism R59022 Diacylglycerol Kinase 2194,

extended description :

Diacylglycerol kinase inhibitor; increases PKC activity

chemical name text :

6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one

formula :

C 27 H 26 FN 3 OS

formula text :

C27H26FN3OS

cas num :

93076-89-2

2020 USD :

155

2021 USD :

162 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage