R 59-022 | Tocris Bioscience 2194/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

R 59-022

catalog :

2194/10

quantity :

10 mg

price :

179 USD

citations: 1

Reference
Conley J, Meyer J, Nuss A, Doyle T, Savinov S, Hill C, et al. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. J Pharmacol Exp Ther. 2015;352:53-60 pubmed publisher

product information

brand :

Tocris

master code :

2194

SKU :

2194/10

product name :

R 59-022

unit size :

10 mg

description :

CaV3.x blocker

target :

Lipid Metabolism Inhibitors

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

459.58

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

R 59-022 is a diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 u M); increases protein kinase C activity. Potentiates thrombin-induced platelet aggregation and induces neutrophil chemotaxis. Inhibits U46619-induced contractions in mouse aorta and porcine coronary artery.

extended description :

Diacylglycerol kinase inhibitor; increases PKC activity

chemical name text :

6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one

formula :

C 27 H 26 FN 3 OS

formula text :

C27H26FN3OS

cas num :

93076-89-2

USD :

167

Jul-22 :

179 USD

product details :

Diacylglycerol kinase inhibitor; increases PKC activity

sizes available :

10 mg (also 50 mg)