NSC 146109 hydrochloride | Tocris Bioscience 2185 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NSC 146109 hydrochloride

catalog :

2185

quantity :

10 mg (also 50 mg)

price :

163 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Calo E, Gu B, Bowen M, Aryan F, Zalc A, Liang J, et al. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. 2018;554:112-117 pubmed publisher

product information

brand :

Tocris

master code :

2185

SKU :

2185/10

product name :

NSC 146109 hydrochloride

description :

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

target :

p53 Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

316.85

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

catalog number base :

2185

product keywords :

Cell-permeable genotype-selective antitumor agent activates p53-dependent transcription p53 Transcription Factors MDM2 p14ARF NSC146109 hydrochloride p53 2185,

extended description :

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

chemical name text :

(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride

formula :

C 17 H 16 N 2 S.HCl

formula text :

C17H16N2S.HCl

cas num :

59474-01-0

2020 USD :

159

2021 USD :

163 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage