BVT 948 | Tocris Bioscience 2176 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BVT 948

catalog :

2176

quantity :

50 mg

price :

717 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Chen W, Walwyn W, Ennes H, Kim H, McRoberts J, Marvizon J. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. Eur J Neurosci. 2014;39:1439-54 pubmed publisher
Hwang B, Chae H, Jeong Y, Lee Y, Noh E, Youn H, et al. Protein tyrosine phosphatase controls breast cancer invasion through the expression of matrix metalloproteinase-9. BMB Rep. 2013;46:533-8 pubmed

product information

brand :

Tocris

master code :

2176

SKU :

2176/50

product name :

BVT 948

description :

Non-competitive protein tyrosine phosphatase inhibitor

target :

Protein Tyrosine Phosphatase Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

241.25

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 u M); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo . Also inhibits several cytochrome P450 isoforms (IC50 10 u M).

catalog number base :

2176

product keywords :

Non-competitive protein tyrosine phosphatase inhibitors inhibits enhances insulin signaling PTP Shp1 Shp2 Protein Tyrosine Phosphatases BVT948 Protein Tyrosine Phosphatases 2176,

extended description :

Non-competitive protein tyrosine phosphatase inhibitor

chemical name text :

4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione

formula :

C 14 H 11 NO 3

formula text :

C14H11NO3

cas num :

39674-97-0

2020 USD :

696

2021 USD :

717 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage