BVT 948 | Tocris Bioscience 2176/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BVT 948

catalog :

2176/10

quantity :

10 mg (also 50 mg)

price :

216 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Chen W, Walwyn W, Ennes H, Kim H, McRoberts J, Marvizon J. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. Eur J Neurosci. 2014;39:1439-54 pubmed publisher
Hwang B, Chae H, Jeong Y, Lee Y, Noh E, Youn H, et al. Protein tyrosine phosphatase controls breast cancer invasion through the expression of matrix metalloproteinase-9. BMB Rep. 2013;46:533-8 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2176

SKU :

2176/10

product name :

BVT 948

description :

Non-competitive protein tyrosine phosphatase inhibitor

target :

Protein Tyrosine Phosphatase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

241.25

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BVT 948 is a non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 u M); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo . Also inhibits several cytochrome P450 isoforms (IC50 10 u M).

product keywords :

Non-competitive protein tyrosine phosphatase inhibitors inhibits enhances insulin signaling PTP Shp1 Shp2 Protein Tyrosine Phosphatases BVT948 Protein Tyrosine Phosphatases 2176,

extended description :

Non-competitive protein tyrosine phosphatase inhibitor

chemical name text :

4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione

formula :

C14H11NO3

formula text :

C14H11NO3

cas num :

39674-97-0

USD :

213

USD 2025 :

216 USD

product details :

Non-competitive protein tyrosine phosphatase inhibitor

more info or order :

Tocris Bioscience product webpage