Tetrabenazine | Tocris Bioscience 2175 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Tetrabenazine

catalog :

2175

quantity :

10 mg (also 50 mg)

price :

169 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2175

SKU :

2175/10

product name :

Tetrabenazine

description :

Potent inhibitor of vesicular monoamine transport

target :

Vesicular Monoamine Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

317.2

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of vesicular monoamine uptake; depletes stores of dopamine, serotonin and noradrenalin. Binds with high affinity (IC50= 3.2 nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors. Causes behavioral depression; inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice. . Deuterated analog also available.

catalog number base :

2175

product keywords :

Potent inhibitors inhibits vesicular monoamine transport depletes noradrenalin stores dopamine 5-HT Noradrenalin Transporter NET Adrenergic Transporters Monoamine Neurotransmitter DAT Dopamine Serotonin SERT reuptake 5-Hydroxytryptamine noradrenaline Dopamine Transporters Adrenergic Transporters 5-HT Transporters Vesicular Monoamine Transporters 2175,

extended description :

Potent inhibitor of vesicular monoamine transport

chemical name text :

(3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one

formula :

C 19 H 27 NO 3

formula text :

C19H27NO3

cas num :

58-46-8

2020 USD :

162

2021 USD :

169 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage