product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Z-DEVD-FMK
catalog :
2166
quantity :
1 mg
price :
342 USD
more info or order :
citations: 7
Reference
Gallagher L, Radhi O, Abdullah M, McCluskey A, Boyd M, Chan E. Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Cell Death Dis. 2017;8:e3014 pubmed publisher
Henson M, Tucker C, Zhao M, Dudek S. Long-term depression-associated signaling is required for an in vitro model of NMDA receptor-dependent synapse pruning. Neurobiol Learn Mem. 2017;138:39-53 pubmed publisher
Wu K, Phuektes P, Kumar P, Goh G, Moreau D, Chow V, et al. Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication. Nat Commun. 2016;7:13150 pubmed publisher
Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, et al. ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer. Oncotarget. 2015;6:9173-88 pubmed
Im aram A, Farrand L, Bae S, Song G, Song Y, Han J, et al. The mTORC2 component rictor contributes to cisplatin resistance in human ovarian cancer cells. PLoS ONE. 2013;8:e75455 pubmed publisher
Plouffe V, Mohamed N, Rivest McGraw J, Bertrand J, Lauzon M, Leclerc N. Hyperphosphorylation and cleavage at D421 enhance tau secretion. PLoS ONE. 2012;7:e36873 pubmed publisher
Woo M, Xue K, Liu J, McBride H, Tsang B. Calpain-mediated processing of p53-associated parkin-like cytoplasmic protein (PARC) affects chemosensitivity of human ovarian cancer cells by promoting p53 subcellular trafficking. J Biol Chem. 2012;287:3963-75 pubmed publisher
product information
brand :
Tocris
master code :
2166
SKU :
2166/1
product name :
Z-DEVD-FMK
description :
Cell-permeable, irreversible caspase-3 inhibitor
target :
Caspase Inhibitors
category :
Peptides
unit size :
1 mg
observed molecular weight :
668.67
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo .
catalog number base :
2166
product keywords :
Cell-permeable irreversible caspase-3 inhibitors inhibits Caspases Proteinases Proteases Caspases 2166,
extended description :
Cell-permeable, irreversible caspase-3 inhibitor
chemical name text :
Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone
formula :
C 30 H 41 FN 4 O 12
formula text :
C30H41FN4O12
2020 USD :
328
2021 USD :
342 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK