Z-DEVD-FMK | Tocris Bioscience 2166/1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Z-DEVD-FMK

catalog :

2166/1

quantity :

1 mg

price :

396 USD

citations: 8

Reference
Rastogi S, Ellinwood S, Augenstreich J, Mayer Barber K, Briken V. Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF. PLoS Pathog. 2021;17:e1009712 pubmed publisher
Gallagher L, Radhi O, Abdullah M, McCluskey A, Boyd M, Chan E. Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Cell Death Dis. 2017;8:e3014 pubmed publisher
Henson M, Tucker C, Zhao M, Dudek S. Long-term depression-associated signaling is required for an in vitro model of NMDA receptor-dependent synapse pruning. Neurobiol Learn Mem. 2017;138:39-53 pubmed publisher
Wu K, Phuektes P, Kumar P, Goh G, Moreau D, Chow V, et al. Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication. Nat Commun. 2016;7:13150 pubmed publisher
Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, et al. ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer. Oncotarget. 2015;6:9173-88 pubmed
Im aram A, Farrand L, Bae S, Song G, Song Y, Han J, et al. The mTORC2 component rictor contributes to cisplatin resistance in human ovarian cancer cells. PLoS ONE. 2013;8:e75455 pubmed publisher
Plouffe V, Mohamed N, Rivest McGraw J, Bertrand J, Lauzon M, Leclerc N. Hyperphosphorylation and cleavage at D421 enhance tau secretion. PLoS ONE. 2012;7:e36873 pubmed publisher
Woo M, Xue K, Liu J, McBride H, Tsang B. Calpain-mediated processing of p53-associated parkin-like cytoplasmic protein (PARC) affects chemosensitivity of human ovarian cancer cells by promoting p53 subcellular trafficking. J Biol Chem. 2012;287:3963-75 pubmed publisher

product information

brand :

Tocris

master code :

2166

SKU :

2166/1

rank :

0.061

product name :

Z-DEVD-FMK

description :

Cell-permeable, irreversible caspase-3 inhibitor

target :

Caspase Inhibitors

category :

Peptides

sizes available :

1 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Z-DEVD-FMK is a cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo .

extended description :

Cell-permeable, irreversible caspase-3 inhibitor

chemical name text :

Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone

formula :

C 30 H 41 FN 4 O 12

formula text :

C30H41FN4O12

cas num :

210344-95-9

USD :

396 USD

product details :

Cell-permeable, irreversible caspase-3 inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.