nTZDpa | Tocris Bioscience 2150 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

nTZDpa

catalog :

2150

quantity :

10 mg (also 50 mg)

price :

183 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2150

SKU :

2150/10

product name :

nTZDpa

description :

Potent, selective PPAR partial agonist

target :

PPAR gamma Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

428.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, selective non-thiazolidinedione PPAR partial agonist (EC50 = 57 nM); produces ~25% maximum efficacy. Antagonizes full agonist activity by ~60% (IC50 ~ 285 nM). Displays no activity at PPAR or PPAR receptors. Produces altered receptor conformation, and regulates adipocyte development and gene expression, in a differential manner to full PPAR agonists. Modulates metabolism and insulin sensitivity without causing cardiac hypertrophy in mice in vivo .

catalog number base :

2150

product keywords :

Potent selective PPAR PPARgamma partial agonists Peroxisome Proliferator-activating Receptors PPARgamma Receptors 2150,

extended description :

Potent, selective PPAR partial agonist

chemical name text :

5-Chloro-1-[(4-chlorophenyl)methyl]-3-(phenylthio)-1H-indole-2-carboxylic acid

formula :

C 22 H 15 Cl 2 NO 2 S

formula text :

C22H15Cl2NO2S

cas num :

118414-59-8

2020 USD :

179

2021 USD :

183 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage