SCS | Tocris Bioscience 2143 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SCS

catalog :

2143

quantity :

50 mg

price :

125 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Villumsen I, Wellendorph P, Smart T. Pharmacological characterisation of murine Î±4Î²1Î´ GABAA receptors expressed in Xenopus oocytes. BMC Neurosci. 2015;16:8 pubmed publisher
Limon A, Reyes Ruiz J, Miledi R. Loss of functional GABA(A) receptors in the Alzheimer diseased brain. Proc Natl Acad Sci U S A. 2012;109:10071-6 pubmed publisher

product information

brand :

Tocris

master code :

2143

SKU :

2143/50

product name :

SCS

description :

Potent GABAA antagonist; 1-subunit selective

target :

GABA-A Receptor Antagonists

category :

Small Molecules

unit size :

50 mg

observed molecular weight :

256.26

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective partial inhibitor of 1-containing GABAA receptors (IC50 values are 4.5, 5.3 and 7.9 nM at 2 1 1 , 2 1 1 and 2 1 2s GABAA receptors respectively). May bind allosterically to a novel site on GABAA receptor.

catalog number base :

2143

product keywords :

Selective GABAA receptor antagonists beta1-subunit-selective Receptors GABAA Receptors 2143,

extended description :

Potent GABAA antagonist; 1-subunit selective

chemical name text :

Salicylidene salicylhydrazide

formula :

C 14 H 12 N 2 O 3

formula text :

C14H12N2O3

cas num :

3232-36-8

2020 USD :

122

2021 USD :

125 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage