[Ala11,D-Leu15]-Orexin B | Tocris Bioscience 2142 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

[Ala11,D-Leu15]-Orexin B

catalog :

2142

quantity :

1 mg

price :

382 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Moore M, Akladious A, Hu Y, Azzam S, Feng P, Strohl K. Effects of orexin 2 receptor activation on apnea in the C57BL/6J mouse. Respir Physiol Neurobiol. 2014;200:118-25 pubmed publisher
Guo Y, Feng P. OX2R activation induces PKC-mediated ERK and CREB phosphorylation. Exp Cell Res. 2012;318:2004-13 pubmed publisher
Shahid I, Rahman A, Pilowsky P. Orexin A in rat rostral ventrolateral medulla is pressor, sympatho-excitatory, increases barosensitivity and attenuates the somato-sympathetic reflex. Br J Pharmacol. 2012;165:2292-303 pubmed publisher
Malherbe P, Borroni E, Gobbi L, Knust H, Nettekoven M, Pinard E, et al. Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor. Br J Pharmacol. 2009;156:1326-41 pubmed publisher

product information

brand :

Tocris

master code :

2142

SKU :

2142/1

product name :

[Ala11,D-Leu15]-Orexin B

description :

Potent and selective OX2 agonist

target :

OX2 Receptor Agonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

2857.28

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.

catalog number base :

2142

product keywords :

Potent selective OX2 receptor agonists Orexin2 Receptors [Ala11D-Leu15]-OrexinB OX2 Receptor 2142,

extended description :

Potent and selective OX2 agonist

formula :

C 120 H 206 N 44 O 35 S

formula text :

C120H206N44O35S

cas num :

532932-99-3

2020 USD :

363

2021 USD :

382 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage