[Ala11,D-Leu15]-Orexin B | Tocris Bioscience 2142/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

[Ala11,D-Leu15]-Orexin B

catalog :

2142/1

quantity :

1 mg

price :

490 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Moore M, Akladious A, Hu Y, Azzam S, Feng P, Strohl K. Effects of orexin 2 receptor activation on apnea in the C57BL/6J mouse. Respir Physiol Neurobiol. 2014;200:118-25 pubmed publisher
Guo Y, Feng P. OX2R activation induces PKC-mediated ERK and CREB phosphorylation. Exp Cell Res. 2012;318:2004-13 pubmed publisher
Shahid I, Rahman A, Pilowsky P. Orexin A in rat rostral ventrolateral medulla is pressor, sympatho-excitatory, increases barosensitivity and attenuates the somato-sympathetic reflex. Br J Pharmacol. 2012;165:2292-303 pubmed publisher
Malherbe P, Borroni E, Gobbi L, Knust H, Nettekoven M, Pinard E, et al. Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor. Br J Pharmacol. 2009;156:1326-41 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2142

SKU :

2142/1

product name :

[Ala11,D-Leu15]-Orexin B

description :

Potent and selective OX2 agonist

target :

OX2 Receptor Agonists

unit size :

1 mg

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

2857.28

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

[Ala11,D-Leu15]-Orexin B is a highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.

product keywords :

Potent selective OX2 receptor agonists Orexin2 Receptors [Ala11D-Leu15]-OrexinB OX2 Receptor 2142,

extended description :

Potent and selective OX2 agonist

formula :

C120H206N44O35S

formula text :

C120H206N44O35S

cas num :

532932-99-3

USD :

475

USD 2025 :

490 USD

product details :

Potent and selective OX2 agonist

more info or order :

Tocris Bioscience product webpage