Amisulpride | Tocris Bioscience 2132 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Amisulpride

catalog :

2132

quantity :

50 mg

price :

131 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Schulz S, Heidmann K, Mike A, Klaft Z, Heinemann U, Gerevich Z. First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors. Br J Pharmacol. 2012;167:1480-91 pubmed publisher
Midkiff J, Borochoff Porte N, White D, Johnson D. Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways. PLoS ONE. 2011;6:e25395 pubmed publisher

product information

brand :

Tocris

master code :

2132

SKU :

2132/50

product name :

Amisulpride

description :

Selective D2 and D3 antagonist; atypical antipsychotic

target :

Non-selective Dopamine Receptor Antagonists

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

369.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, selective dopamine D2 and D3 receptor antagonist. Ki values are 2.8 and 3.2 nM respectively for human D2 and D3 and 1000 nM for human D1, D4 and D5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D2/D3 receptors at higher doses. Preferentially interacts with limbic D2-like receptors in vivo . Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.

catalog number base :

2132

product keywords :

Selective D2/D3 receptor antagonists atypical antipsychotic agent Dopamine D2-like Non-Selective Receptors dopaminergic DAN2163 DAN 2163 Non-selective Dopamine 2132,

extended description :

Selective D2 and D3 antagonist; atypical antipsychotic

chemical name text :

4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-benzamide

formula :

C 17 H 27 N 3 O 4 S

formula text :

C17H27N3O4S

cas num :

71675-85-9

2020 USD :

128

2021 USD :

131 USD

alt names :

DAN 2163

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage