PNU 37883 hydrochloride | Tocris Bioscience 2095/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PNU 37883 hydrochloride

catalog :

2095/10

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2095

SKU :

2095/10

product name :

PNU 37883 hydrochloride

description :

Vascular Kir6 (KATP) channel blocker

target :

Inward Rectifier Potassium Channel Blockers

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Desiccate at RT

observed molecular weight :

381.98

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PNU 37883 hydrochloride is a novel antagonist selective for the vascular form of Kir6 (KATP) channel; inhibits Kir6 currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. Inhibits blood vessel relaxation and hypotension induced by pinacidil in vivo . Displays weak diuretic effects.

product keywords :

Vascular KATP channels blockers Potassium KIR Inward Rectifier K+ PNU37883 hydrochloride antagonist Kir6 Inward rectifier Potassium Channels 2095,

extended description :

Vascular Kir6 (KATP) channel blocker

chemical name text :

N-Cyclohexyl-N -tricyclo[3.3.1.13,7]dec-1-yl-4-morpholinecarboximidamide hydrochloride

formula :

C21H35N3O.HCl

formula text :

C21H35N3O.HCl

cas num :

57568-80-6

USD :

210

USD 2025 :

189 USD

product details :

Vascular Kir6 (KATP) channel blocker

more info or order :

Tocris Bioscience product webpage