CALP1 | Tocris Bioscience 2090 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CALP1

catalog :

2090

quantity :

1 mg

price :

169 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Ferdek P, Jakubowska M, Nicolaou P, Gerasimenko J, Gerasimenko O, Petersen O. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides. Cell Death Dis. 2017;8:e2640 pubmed publisher
Tzeng B, Chen Y, Huang C, Lin S, Lee K, Chen C. The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice. Cardiovasc Res. 2012;96:533-42 pubmed publisher

product information

brand :

Tocris

master code :

2090

SKU :

2090/1

product name :

CALP1

description :

Cell-permeable calmodulin agonist

target :

Calcium Binding Protein Modulator Agonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

842.09

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 u M). Shown to protect pancreatic acinar cells from gossypol (Cat.No. 1964) induced necrosis. Inhibits VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo .

catalog number base :

2090

product keywords :

Cell-permeable calmodulin agonists inhibitors inhibits Ca2+-sensitive ion channels Ca2+ Binding Protein modulators Calcium Signaling Signalling Calcium-like peptide1 Calcium-like peptide 1 Calcium Binding Protein Other Channel Modulators 2090,

extended description :

Cell-permeable calmodulin agonist

formula :

C 40 H 75 N 9 O 10

formula text :

C40H75N9O10

cas num :

145224-99-3

2020 USD :

164

2021 USD :

169 USD

alt names :

Calcium-like peptide 1

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage