Exendin-3 (9-39) amide | Tocris Bioscience 2081 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Exendin-3 (9-39) amide

catalog :

2081

quantity :

1 mg

price :

441 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Bauer P, Duca F, Waise T, Dranse H, Rasmussen B, Puri A, et al. Lactobacillus gasseri in the Upper Small Intestine Impacts an ACSL3-Dependent Fatty Acid-Sensing Pathway Regulating Whole-Body Glucose Homeostasis. Cell Metab. 2018;27:572-587.e6 pubmed publisher
Tuesta L, Chen Z, Duncan A, Fowler C, Ishikawa M, Lee B, et al. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 2017;20:708-716 pubmed publisher
Maniscalco J, Zheng H, Gordon P, Rinaman L. Negative Energy Balance Blocks Neural and Behavioral Responses to Acute Stress by "Silencing" Central Glucagon-Like Peptide 1 Signaling in Rats. J Neurosci. 2015;35:10701-14 pubmed publisher
Gaitonde S, Kohli R, Seeley R. The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition. J Surg Res. 2012;178:33-9 pubmed publisher

product information

brand :

Tocris

master code :

2081

SKU :

2081/1

product name :

Exendin-3 (9-39) amide

description :

Potent GLP-1 receptor antagonist

target :

Glucagon-Like Peptide 1 Receptor Antagonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

3369.79

url print :

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details of functionality :

Potent and selective GLP-1 receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Inhibits cAMP production and insulin release induced by GLP-1 (7-36), exendin-3 (IC50 = 20 nM) and exendin-4. Blocks the inhibitory effect of GLP-1 on food intake in rats.

catalog number base :

2081

product keywords :

Potent GLP-1 receptor antagonists Receptors Glucagon-Like Peptide 1 Glucagon-Like Peptide 1 Receptors 2081,

extended description :

Potent GLP-1 receptor antagonist

formula :

C 149 H 234 N 40 O 47 S

formula text :

C149H234N40O47S

cas num :

133514-43-9

2020 USD :

432

2021 USD :

441 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage