Exendin-3 (9-39) amide | Tocris Bioscience 2081/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Exendin-3 (9-39) amide

catalog :

2081/1

quantity :

1 mg

price :

579 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Bauer P, Duca F, Waise T, Dranse H, Rasmussen B, Puri A, et al. Lactobacillus gasseri in the Upper Small Intestine Impacts an ACSL3-Dependent Fatty Acid-Sensing Pathway Regulating Whole-Body Glucose Homeostasis. Cell Metab. 2018;27:572-587.e6 pubmed publisher
Tuesta L, Chen Z, Duncan A, Fowler C, Ishikawa M, Lee B, et al. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 2017;20:708-716 pubmed publisher
Maniscalco J, Zheng H, Gordon P, Rinaman L. Negative Energy Balance Blocks Neural and Behavioral Responses to Acute Stress by "Silencing" Central Glucagon-Like Peptide 1 Signaling in Rats. J Neurosci. 2015;35:10701-14 pubmed publisher
Ho J, Anekonda V, Thompson B, Zhu M, Curry R, Hwang B, et al. Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats. Endocrinology. 2014;155:2845-57 pubmed publisher
Gaitonde S, Kohli R, Seeley R. The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition. J Surg Res. 2012;178:33-9 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2081

SKU :

2081/1

product name :

Exendin-3 (9-39) amide

description :

Potent GLP-1 receptor antagonist

target :

Glucagon-Like Peptide 1 Receptor Antagonists

unit size :

1 mg

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

3369.79

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Exendin-3 (9-39) amide is a potent and selective GLP-1 receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Inhibits cAMP production and insulin release induced by GLP-1 (7-36), exendin-3 (IC50 = 20 nM) and exendin-4. Blocks the inhibitory effect of GLP-1 on food intake in rats.

product keywords :

Potent GLP-1 receptor antagonists Receptors Glucagon-Like Peptide 1 Glucagon-Like Peptide 1 Receptors 2081,

extended description :

Potent GLP-1 receptor antagonist

formula :

C149H234N40O47S

formula text :

C149H234N40O47S

cas num :

133514-43-9

USD :

555

USD 2025 :

579 USD

product details :

Potent GLP-1 receptor antagonist

more info or order :

Tocris Bioscience product webpage