Exendin-3 (9-39) amide | Tocris Bioscience 2081/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Exendin-3 (9-39) amide

catalog :

2081/1

quantity :

1 mg

price :

579 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Bauer P, Duca F, Waise T, Dranse H, Rasmussen B, Puri A, et al. Lactobacillus gasseri in the Upper Small Intestine Impacts an ACSL3-Dependent Fatty Acid-Sensing Pathway Regulating Whole-Body Glucose Homeostasis. Cell Metab. 2018;27:572-587.e6 pubmed publisher
Tuesta L, Chen Z, Duncan A, Fowler C, Ishikawa M, Lee B, et al. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 2017;20:708-716 pubmed publisher
Maniscalco J, Zheng H, Gordon P, Rinaman L. Negative Energy Balance Blocks Neural and Behavioral Responses to Acute Stress by "Silencing" Central Glucagon-Like Peptide 1 Signaling in Rats. J Neurosci. 2015;35:10701-14 pubmed publisher
Ho J, Anekonda V, Thompson B, Zhu M, Curry R, Hwang B, et al. Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats. Endocrinology. 2014;155:2845-57 pubmed publisher
Gaitonde S, Kohli R, Seeley R. The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition. J Surg Res. 2012;178:33-9 pubmed publisher

product information

brand :

Tocris

catalog number base :

2081

SKU :

2081/1

product name :

Exendin-3 (9-39) amide

units size :

1 mg

description :

Potent GLP-1 receptor antagonist

target :

Glucagon-Like Peptide 1 Receptor Antagonists

category :

Peptides

purity :

95%

observed molecular weight :

3369.79

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Exendin-3 (9-39) amide is a potent and selective GLP-1 receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Inhibits cAMP production and insulin release induced by GLP-1 (7-36), exendin-3 (IC50 = 20 nM) and exendin-4. Blocks the inhibitory effect of GLP-1 on food intake in rats.

top caption :

Potent GLP-1 receptor antagonist

extended description :

Potent GLP-1 receptor antagonist

formula :

C149H234N40O47S

formula text :

C149H234N40O47S

cas num :

133514-43-9

USD :

579 USD

product details :

Potent GLP-1 receptor antagonist

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage