Aminopurvalanol A | Tocris Bioscience 2072 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Aminopurvalanol A

catalog :

2072

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Teo R, Möhrlen F, Plickert G, Müller W, Frank U. An evolutionary conserved role of Wnt signaling in stem cell fate decision. Dev Biol. 2006;289:91-9 pubmed

product information

brand :

Tocris

master code :

2072

SKU :

2072/10

product name :

Aminopurvalanol A

description :

Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

403.91

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 20 - 35 nM for cdk1, cdk2 and cdk5). Also inhibits ERK1 (IC50 = 12.0 M) and ERK2 (IC50 = 3.1 M) and is 3000-fold selective over a range of other protein kinases (IC50 100 M). Arrests cell cycle at G2/M boundary (IC50 = 1.25 M), and induces apoptosis at concentrations 10 M. Cell permeable.

catalog number base :

2072

product keywords :

Cyclin-dependent protein kinases inhibitors inhibits Cdk AminopurvalanolA NG97 NG 97 Cyclin-dependent Kinase 2072,

extended description :

Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5

chemical name text :

(2R)-2-[[6-[(3-Amino-5-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol

formula :

C 19 H 26 ClN 7 O

formula text :

C19H26ClN7O

cas num :

220792-57-4

2020 USD :

225

2021 USD :

225 USD

alt names :

NG 97

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage