Antisauvagine-30 | Tocris Bioscience 2071 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Antisauvagine-30

catalog :

2071

quantity :

1 mg

price :

465 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Narla C, Dunn H, Ferguson S, Poulter M. Suppression of piriform cortex activity in rat by corticotropin-releasing factor 1 and serotonin 2A/C receptors. Front Cell Neurosci. 2015;9:200 pubmed publisher
Zhao Shea R, DeGroot S, Liu L, Vallaster M, Pang X, Su Q, et al. Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal. Nat Commun. 2015;6:6770 pubmed publisher

product information

brand :

Tocris

master code :

2071

SKU :

2071/1

product name :

Antisauvagine-30

description :

Potent, selective and competitive CRF2 antagonist

target :

CRF2 Receptor Antagonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

3650.29

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2 and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2 cells (pA2 = 8.49). Prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo .

catalog number base :

2071

product keywords :

Potent selective competitive CRF2 antagonists Corticotropin-Releasing Factor2 Receptors [D-Phe11,His12]-Sauvagine (11-40) CRF2 Receptors 2071,

extended description :

Potent, selective and competitive CRF2 antagonist

formula :

C 161 H 274 N 48 O 46 S

formula text :

C161H274N48O46S

cas num :

220673-95-0

2020 USD :

447

2021 USD :

465 USD

alt names :

[ D-Phe11,His12]-Sauvagine (11-40)

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage