K 41498 | Tocris Bioscience 2070 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

K 41498

catalog :

2070

quantity :

1 mg

price :

450 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Nakamura T, Sapru H. Cardiovascular responses to microinjections of urocortins into the NTS: role of inotropic glutamate receptors. Am J Physiol Heart Circ Physiol. 2009;296:H2022-9 pubmed publisher

product information

brand :

Tocris

master code :

2070

SKU :

2070/1

product name :

K 41498

description :

Highly selective and potent CRF2 antagonist

target :

CRF2 Receptor Antagonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

3632.26

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2 , CRF2 and CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in hCRF2 - and hCRF2 -expressing cells. In rats in vivo , blocks urocortin-induced hypotension following systemic administration.

catalog number base :

2070

product keywords :

selective potent CRF2 antagonists Corticotropin-Releasing Factor2 Receptors K41498 CRF2 Receptors 2070,

extended description :

Highly selective and potent CRF2 antagonist

formula :

C 162 H 276 N 48 O 46

formula text :

C162H276N48O46

cas num :

434938-41-7

2020 USD :

432

2021 USD :

450 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage