product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Pentostatin
catalog :
2033/10
quantity :
10 mg (also 50 mg)
price :
197 USD
more info or order :
citations: 6
Reference
Song A, Zhang Y, Han L, Yegutkin G, Liu H, Sun K, et al. Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun. 2017;8:14108 pubmed publisher
Ledderose C, Hefti M, Chen Y, Bao Y, Seier T, Li L, et al. Adenosine arrests breast cancer cell motility by A3 receptor stimulation. Purinergic Signal. 2016;12:673-685 pubmed
Li G, Nakagome I, Hirono S, Itoh T, Fujiwara R. Inhibition of adenosine deaminase (ADA)-mediated metabolism of cordycepin by natural substances. Pharmacol Res Perspect. 2015;3:e00121 pubmed publisher
Eckle T, Hughes K, Ehrentraut H, Brodsky K, Rosenberger P, Choi D, et al. Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury. FASEB J. 2013;27:3078-89 pubmed publisher
Weng T, Karmouty Quintana H, Garcia Morales L, Molina J, Pedroza M, Bunge R, et al. Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease. FASEB J. 2013;27:2013-26 pubmed publisher
Kucerova L, Broz V, Fleischmannova J, Santruckova E, Sidorov R, Dolezal V, et al. Characterization of the Drosophila adenosine receptor: the effect of adenosine analogs on cAMP signaling in Drosophila cells and their utility for in vivo experiments. J Neurochem. 2012;121:383-95 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2033
SKU :
2033/10
product name :
Pentostatin
description :
Adenosine deaminase inhibitor
target :
Deaminase Inhibitors
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Store at +4°C
observed molecular weight :
268.27
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Pentostatin is an irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). Anticancer agent.
product keywords :
adenosines deaminases inhibitors inhibits antimetabolites chemotherapeutics Deoxycoformycin Deaminases 2033,
extended description :
Adenosine deaminase inhibitor
chemical name text :
(8R)-3-(2-Deoxy- -D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
formula :
C11H16N4O4
formula text :
C11H16N4O4
cas num :
53910-25-1
USD :
189
USD 2025 :
197 USD
product details :
Adenosine deaminase inhibitor
alt names :
Deoxycoformycin
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK