Ch 55 | Tocris Bioscience 2020 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ch 55

catalog :

2020

quantity :

10 mg (also 50 mg)

price :

171 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Dhandapani L, Yue P, Ramalingam S, Khuri F, Sun S. Retinoic acid enhances TRAIL-induced apoptosis in cancer cells by upregulating TRAIL receptor 1 expression. Cancer Res. 2011;71:5245-54 pubmed publisher

product information

brand :

Tocris

master code :

2020

SKU :

2020/10

product name :

Ch 55

description :

Potent RAR agonist

target :

Retinoic Acid Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

364.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Highly potent synthetic retinoid that has high affinity for RAR- and RAR- receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM).

catalog number base :

2020

product keywords :

Potent retinoic acid receptors RAR agonists Ch55 Retinoic Acid Receptors 2020,

extended description :

Potent RAR agonist

chemical name text :

4-[(1E)-3-[3,5-bis(1,1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid

formula :

C 24 H 28 O 3

formula text :

C24H28O3

cas num :

110368-33-7

2020 USD :

166

2021 USD :

171 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage