Ch 55 | Tocris Bioscience 2020/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ch 55

catalog :

2020/10

quantity :

10 mg (also 50 mg)

price :

220 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Li X, Liu D, Ma Y, Du X, Jing J, Wang L, et al. Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State. Cell Stem Cell. 2017;21:264-273.e7 pubmed publisher
Dhandapani L, Yue P, Ramalingam S, Khuri F, Sun S. Retinoic acid enhances TRAIL-induced apoptosis in cancer cells by upregulating TRAIL receptor 1 expression. Cancer Res. 2011;71:5245-54 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2020

SKU :

2020/10

product name :

Ch 55

description :

Potent RAR agonist

target :

Retinoic Acid Receptor Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

364.47

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ch 55 is a highly potent synthetic retinoid that has high affinity for RAR- and RAR- receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM). . For more information about how Ch 55 may be used, see our protocol: Highly Efficient Generation of CiPSCs from MEFs

product keywords :

Potent retinoic acid receptors RAR agonists Ch55 Retinoic Acid Receptors 2020,

extended description :

Potent RAR agonist

chemical name text :

4-[(1E)-3-[3,5-bis(1,1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid

formula :

C24H28O3

formula text :

C24H28O3

cas num :

110368-33-7

USD :

213

USD 2025 :

220 USD

product details :

Potent RAR agonist

more info or order :

Tocris Bioscience product webpage