PSB 36 | Tocris Bioscience 2019 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PSB 36

catalog :

2019

quantity :

50 mg

price :

788 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Cheng R, Segala E, Robertson N, Deflorian F, DorÃ© A, Errey J, et al. Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity. Structure. 2017;25:1275-1285.e4 pubmed publisher
Ziemli ska E, K gler S, Schachner M, Wewi r I, Czarkowska Bauch J, Skup M. Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats. PLoS ONE. 2014;9:e88833 pubmed publisher
Arnal A, Gore J, Rudkin A, Bartlett D, Leiter J. Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering-Breuer inflation reflex in unanesthetized rat pups. Respir Physiol Neurobiol. 2013;186:73-80 pubmed publisher
Carlström M, Wilcox C, Welch W. Adenosine A(2) receptors modulate tubuloglomerular feedback. Am J Physiol Renal Physiol. 2010;299:F412-7 pubmed publisher
Guerreiro S, Toulorge D, Hirsch E, Marien M, Sokoloff P, Michel P. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008;74:980-9 pubmed publisher

product information

brand :

Tocris

master code :

2019

SKU :

2019/50

product name :

PSB 36

description :

Potent and selective A1 antagonist

target :

Adenosine A1 Receptor Antagonists

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

386.49

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective A1 adenosine receptor antagonist. Displays binding affinities of 0.12, 187, 552, 6500 and 2300 nM for rA1, hA2B, rA2A, rA3 and hA3 receptors respectively. Demonstrates greater selectivity than DPCPX (Cat. No. 0439).

catalog number base :

2019

product keywords :

Potent selective A1 antagonists Receptors adenosines PSB36 Adenosine A1 Receptors 2019,

extended description :

Potent and selective A1 antagonist

chemical name text :

1-Butyl-8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-3-(3-hydroxypropyl)-1H-purine-2,6-dione

formula :

C 21 H 30 N 4 O 3

formula text :

C21H30N4O3

cas num :

524944-72-7

2020 USD :

765

2021 USD :

788 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage