Mirtazapine | Tocris Bioscience 2018 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Mirtazapine

catalog :

2018

quantity :

10 mg (also 50 mg)

price :

125 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Otvos R, Iyer J, van Elk R, Ulens C, Niessen W, Somsen G, et al. Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Toxins (Basel). 2015;7:2336-53 pubmed publisher
Midkiff J, Borochoff Porte N, White D, Johnson D. Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways. PLoS ONE. 2011;6:e25395 pubmed publisher

product information

brand :

Tocris

master code :

2018

SKU :

2018/10

product name :

Mirtazapine

description :

Potent 5-HT2 antagonist; also 5-HT3, H1 and 2 antagonist; antidepressant

target :

Non-selective 5-HT2 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

265.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent 2-adrenoceptor antagonist (pKi values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of 2-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pKi values are 5.6, 5 and 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo .

catalog number base :

2018

product keywords :

Potent 5-HT3 antagonists 5-HT2 H1 2-adrenoceptor alpha2-adrenoceptor a2-adrenoceptor 2-Adrenergic alpha2-Adrenergic a2-adrenergic Antidepressant Serotonin Receptors Non-Selective Histamine histaminergic Org3770 Org 3770 6-Azamianserin Non-selective 5-HT2 5-HT3 Receptors Histamine H1 Receptors Adrenergic Alpha-2 Receptors 2018,

extended description :

Potent 5-HT2 antagonist; also 5-HT3, H1 and 2 antagonist; antidepressant

chemical name text :

1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine

formula :

C 17 H 19 N 3

formula text :

C17H19N3

cas num :

85650-52-8

2020 USD :

120

2021 USD :

125 USD

alt names :

Org 3770, 6-Azamianserin

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage